A Proliferation-Inducing Ligand ELISA (APRIL ELISA)

$1,944.00
Catalog
30-9411

The A Proliferation-Inducing Ligand ELISA (APRIL ELISA) is for Research Use Only and not for use in diagnostic procedures. 

Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
15.6 - 1000 ng/mL
Sensitivity
15.6 ng/mL
Sizes
96 Wells
Sample Types
Cell Culture, Plasma
Inc Time Hour
6
Inc Time Minute
20
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
100
Detection
Colorimetric

APRIL - a type II transmembrane protein [250 aa, cytoplasmatic domain: 28aa, transmembrane domain: 21aa, extracellular domain: 201aa] is considered to be involved in autoimmune and cancer diseases. It stimulates proliferation of tumor cell lines and seems to play a role in tumorgenesis. In general it is involved in B and T cell proliferation, triggers humoral immune responses, activates NF-κB and induces cell death.

TACI (transmembrane activator) and BCMA (B-cell maturation antigen) are considered to be receptors for APRIL. APRIL belongs to the TNF-Superfamily which is involved in immune responses and apoptosis.

A Proliferation-Inducing Ligand ELISA (APRIL ELISA)

30-9411

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