Adipocyte Fatty Acid Binding Protein ELISA (AFABP ELISA)

$1,381.00
Catalog
32-5181
Research Use Only. Not for Use in Diagnostic Procedures.
Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
0.5 - 25 ng/mL
Sensitivity
0.1 ng/mL
Sizes
96 Wells
Sample Types
Cell Culture, Plasma, Serum
Inc Time Hour
2
Inc Time Minute
30
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
20
Detection
Colorimetric

Adipocyte Fatty Acid Binding Protein (AFABP) is a 15 kDa member of the intracellular Fatty Acid Binding Protein (FABP) family, which is known for the ability to bind fatty acids and related compounds. AFABP is expressed in a tissue specific-manner in differentiated adipocytes and is a critical gene in the regulation of the biological function of these cells. According to some results, AFABP may be involved in mediating obesity-induced alterations in adipocyte gene expression. In macrophages AFABP modulates inflammatory responses and cholesterol ester accumulation, and total or macrophage-specific AFABP deficiency confers dramatic protection against atherosclerosis in the apoE-/- mice. These results indicate a central role for AFABP in the development of major components of the metabolic syndrome through its distinct actions in adipocytes and macrophages. Besides being active within the cell, AFAB appears to be a secreted protein, with unknown function.

Adipocyte Fatty Acid Binding Protein ELISA (AFABP ELISA)

32-5181

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