The Anti-LC1 ELISA is intended for the quantitative and qualitative determination of anti-liver cytosol type 1 autoantibodies in human serum. - Ready-to-use controls and calibrators - Results in only 90 minutes Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
0 - 300 U/mL
Sensitivity
1.0 U/mL
Sizes
96 Wells
Sample Types
Serum
Inc Time Hour
1
Inc Time Minute
35
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
10
Detection
Colorimetric
Serum samples diluted 1:101 are incubated in the microplates coated with the specific antigen. Anti
LC-1 antibodies, if present in the sample, bind to the antigen. The unbound fraction is washed off in
the following step. Afterwards anti-human immunoglobulins conjugated to horseradish peroxidase
(conjugate) are incubated and react with the antigen-antibody complex of the samples in the
microplates. Unbound conjugate is washed off in the following step. Addition of TMB-substrate
generates an enzymatic colorimetric (blue) reaction, which is stopped by diluted acid (color changes
to yellow). The rate of color formation from the chromogen is a function of the amount of conjugate
bound to the antigen-antibody complex and this is proportional to the initial concentration of the
respective antibodies in the sample.
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