The Mouse Serum Amyloid P ELISA (Mouse SAP ELISA) is a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring SAP in serum and plasma of mice. Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
6.25 200 ng/mL
Sensitivity
12.5 ng/mL
Sizes
96 Wells
Sample Types
Plasma, Serum
Inc Time Hour
2
Inc Time Minute
10
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
5
Detection
Colorimetric
Mouse serum amyloid P (SAP) is a major acute phase protein that circulates as a ~230 kDa glycoprotein. It is composed of 10 identical subunits arranged as two cyclic pentameric discs and contains ~10% carbohydrate. Basal levels of SAP may vary significantly in different inbred mouse strains but SAP is a major acute phase protein in all strains. During acute chemical, physical, or inflammatory stimulus, its concentration can increase 50-100 fold within 24-48 hours. Changes can readily be detected in 4-6 hours. Measurement of the concentration of SAP is indicative of the extent and severity of an inflammatory stimulus and can be used to assess various modalities of treatment.
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