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Endocrinology

Vasopressin: An Important Biomarker for Water Metabolism & Sleep Research
April 21, 2023

Vasopressin: An Important Biomarker for Water Metabolism & Sleep Research

ALPCO is pleased to announce the addition of two new radioimmunoassays (RIA) to measure vasopressin. The Vasopressin RIA and the Vasopressin Direct RIA. Both assays were originally developed by BÜHLMANN Laboratories. After optimization for greater ease-of-use, they are now offered by NovoLytiX GmbH of Switzerland. ALPCO is proud to be the exclusive distributor for the Vasopressin RIA and Va...
Circadian Rhythm and Obesity: The Role of the Body’s Clocks in Metabolic Disorders
April 21, 2023

Circadian Rhythm and Obesity: The Role of the Body’s Clocks in Metabolic Disorders

800 million people worldwide struggle with obesity, a disease poised to cost over $1 trillion in medical consequences by 2025. Over 40% of the US population is impacted, according to the Centers for Disease Control. Obesity is a major risk factor in the development of illnesses that lead to diabetes, such as insulin resistance, hypertension, and other metabolic disorders. Long-term disrupti...
Role of Energy Homeostasis in Diabetes
April 20, 2023

Understanding the Role of Energy Homeostasis in Diabetes

Introduction The prevalence of diabetes and obesity has been on the rise for several decades and research has demonstrated that other parts of the body, including the cardiovascular system and kidneys, can be affected by diabetes. The key to understanding the relationship between diabetes and these other areas begins with the role of energy homeostasis in diabetes. At the same time, investig...
Understanding Exocrine Pancreatic Insufficiency
May 19, 2022

Understanding Exocrine Pancreatic Insufficiency

Pancreatic Elastase (PE) Testing for Determination of Exocrine Pancreatic Insufficiency (EPI) Advantages of ALPCO PE Testing for Determination of EPI • No interference from PERT • Single sample collection without dietary restriction • Detection of both CELA3A and CELA3B isoforms • Compatibility with current clinical cut-offs • FDA Class I Device. For In Vitro Diagnostic Use. • Accura...
Iron Regulation and Homeostasis: Kits to Study Regulatory Proteins
March 25, 2022

Iron Regulation and Homeostasis: Kits to Study Regulatory Proteins

Iron Homeostasis Iron is a trace element required for several critical cellular processes. Too little iron (anemia) or too much iron (iron overload) can be harmful. While there is no known mechanism for the controlled excretion of excess iron, a handful of regulatory proteins control the absorption, transport, and storage of iron to maintain homeostasis.1,2 ALPCO offers several kits for the ...
Melatonin Products for Sleep Disorder-Related Research
January 18, 2022

Melatonin Products for Sleep Disorder-Related Research

Melatonin is an endogenously expressed hormone present in a wide spectrum of organisms from bacteria to humans.  Primarily secreted by the pineal gland, melatonin enters the circulation via cerebrospinal fluid and plays a key role in the regulation of the sleep-wake cycle.  Melatonin levels help modulate mood, reproduction, and immune system activities.  The rise and fall of circulating level...
An Accurate Solution to the Challenges with Measuring GLP-1
July 31, 2018

An Accurate Solution to the Challenges with Measuring GLP-1

Glucagon-like peptide-1 (GLP-1) is a gut hormone which plays an essential role in insulin secretion and glucose homeostasis1. While GLP-1 has become central to many metabolic disease research programs, various GLP-1 ELISA kits currently available on the market have been failing to meet the needs of researchers1-5. Therefore, measuring total and active levels of GLP-1 is difficult for many labs2...
Endocrine Disrupting Chemicals and Biomarkers of EDC
October 12, 2016

Endocrine Disrupting Chemicals and Biomarkers

Introduction Humans and the environment are exposed to numerous chemicals every day1. Each year, about 2,000 new chemicals are manufactured in the U.S.2. Research findings over the years have shown how some chemicals known as endocrine disrupting chemicals (EDCs) can interact with the endocrine system, disrupt homeostasis, and lead to issues such as obesity and sterility1. As a result, endocri...
Regulating Endocrine Disrupting Chemicals
September 27, 2016

Regulating Endocrine Disrupting Chemicals in Consumer Products

Date: September 27, 2016 Author: Andrea Tarbet, Product Marketing Associate at ALPCO From cosmetics to water bottles, endocrine disrupting chemicals (EDCs) have surfaced in our everyday lives. EDCs are compounds that can interfere with the endocrine system’s ability to help an organism develop, grow, reproduce, and maintain overall homeostasis1.  Since EDCs are found nearly everywhere, we...
ALPCO Releases a New Broad Range Periostin ELISA
June 7, 2016

ALPCO Releases a New Broad Range Periostin ELISA

ALPCO is now offering a new broad range Periostin ELISA that has been optimized to detect all known splicing forms of human periostin. The Periostin ELISA is highly characterized with a full validation package, and offers great reproducibility and precision. Not only are all standards and controls included with the kit, but it can be automated, making the assay both cost effective and flexible ...