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Gastrointestinal (GI) pathogens consist of bacterial, viral, and parasitic groups. Bacterial, viral, and parasitic pathogens are caused by direct contact, indirect contact, and contaminated food and water. The most common pathogen is viral, which infects a host by introducing genetic material into the cell to produce more virus particles. Once the host cell bursts, the virus particles will then continue to infect other cells. Bacteria, once ingested, will continue to reproduce by binary fission; an asexual reproduction by a separation of the body into two new bodies. Parasites attach and thrive off their host, growing at a high rate. Symptoms of gastrointestinal pathogens include fever, abdominal cramps, nausea, muscle aches, headaches, and diarrhea. GI pathogen panels are used to test for the presence of multiple disease-causing pathogens in stool samples. ALPCO offers both DNA and RNA real-time polymerase chain reaction (PCR/RT-PCR) solutions for the detection and/or differentiation of pathogens.

Key Features:

• Rapid Results: Results in less than 1.5 hours
• Complete Kits: Includes positive, negative, and internal controls
• Flexibility: Assays are run on commonly used real-time PCR instruments
• Reliability: Produces consistent and accurate results

Viral Gastrointestinal Pathogens:

 Fig. 1: Common Viral Gastrointestinal Pathogens

• Our offering includes the most common viral pathogens (norovirus, rotavirus, and adenovirus).

 Table 1: Viral Gastrointestinal Pathogen RT-PCR Kits

Product Name	Product Code	Target
Hospital Stool Panel RT-PCR Kit	86-HSPHU-100	Norovirus GI & GII; Rotavirus; C. difficile toxin genes A/B
Norovirus RT-PCR Kit	86-NVIHU-100	Norovirus GI & GII
Norovirus I & II RT-PCR Kit	86-NV2HU-100	Norovirus GI; Norovirus GII
Viral Stool Panel I RT-PCR Kit	86-VS1HU-100	Norovirus; Rotavirus; Adenovirus 40/41; Astrovirus
Viral Stool Panel II RT-PCR Kit	86-VS2HU-100	Rotavirus; Astrovirus; Adenovirus 40/41

 

Bacterial Gastrointestinal Pathogens:

Fig. 2: Common Bacterial Gastrointestinal Pathogens

• Our offering includes the most common bacterial pathogens (Escherichia coli and Campylobacter spp.).
• The importance of differentiation between Enterotoxigenic E. coli (ETEC), Enteropathogenic E. coli (EPEC), Enterohemorrhagic E. coli (EHEC), Enteroinvasive E. coli (EIEC), and Enteroaggregative E. coli (EAEC) is to determine the correct therapy as E. coli varies between each strain.

Table 2: Bacterial Gastrointestinal PCR Kits

Product Name	Product Code	Target
Bacterial Stool Panel I PCR Kit	86-BS1HU-100	Shiga toxin-producing E. coli (STEC); Salmonella spp., Enteroinvasive E. coli (EIEC)/Shigella spp.; Campylobacter spp.
Bacterial Stool Panel PCR Kit	86-BSHU-100	Campylobacter spp.; Salmonella spp.; Yersinia enterocolitica
EAEC PCR Kit	86-EECHU-100	Enteroaggregative E. coli (EAEC)
ETEC/EIEC PCR Kit	86-ETIHU-100	Enterotoxigenic E. coli (ETEC); Enteroinvasive E. coli (EIEC)/Shigella spp.
E. coli Stool Panel I PCR Kit	86-ECPHU-100	Enterohemorrhagic E. coli (EHEC); Shiga toxin-producing E. coli (STEC); Enteropathogenic E. coli (EPEC)
EHEC/EPEC PCR Kit	86-EHPHU-100	E. coli (Enterohemorrhagic E. coli (EHEC), Enteropathogenic E. coli (EPEC), Shiga toxin-producing E. coli (STEC), Enteroinvasive E. coli (EIEC)/Shigella spp.)
Clostridium Difficile PCR Kit	86-CDFHU-100	C. difficile; C. difficile toxin genes A/B

 

Parasitic Gastrointestinal Pathogens:

Fig. 3: Common Parasitic Gastrointestinal Pathogens

• Our offering includes the most common parasitic pathogen found in North America (Giardia).

Table 3: Parasitic Gastrointestinal PCR Kits

Product Name	Product Code	Target
Dientamoeba fragilis PCR Kit	86-DFGHU-100	D. fragilis
Parasitic Stool Panel I PCR Kit	86-PS1HU-100	G. lamblia; Cryptosporidium spp.; E. histolytica; D. fragilis
Parasitic Stool Panel II PCR Kit	86-PS2HU-100	G. lamblia; Cryptosporidium spp.; E. histolytica

 

Datasheet: Molecular Testing for Gastrointestinal Pathogens Download

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