The Bioactive Sclerostin ELISA is a quantitative immunoassay for the determination of bioactive sclerostin in human serum, EDTA plasma or citrate plasma samples. Sclerostin is a 22.5 kDa secreted glycoprotein that is almost exclusively produced in osteocytes and functions as a potent inhibitor of Wnt signaling. Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
10-320 pmol/l
Sensitivity
LLOQ: 1.3 pmol/l
Sizes
96 Wells
Sample Types
Citrate Plasma, EDTA Plasma, Serum
Inc Time Hour
3
Inc Time Minute
30
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
20
Detection
Colorimetric
The human bioactive Sclerostin immunoassay is a 3.5 hour, 96-well, sandwich ELISA for the quantitative
determination of bioactive Sclerostin in human serum, EDTA plasma, and citrate plasma. The assay employs
human based serum standards to ensure biological reliable data. The antibody characterization of both antibodies utilized in this assay comprises epitope mapping, binding kinetics, and determination of antibody purity.
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