Anti-Insulin-G EIA is a solid phase enzyme immunoassay employing recombinant human insulin for the quantitative and qualitative detection of antibodies against human insulin in human serum. Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
3 - 300 U/mL
Sensitivity
1 U/mL
Sizes
96 Wells
Sample Types
Serum
Inc Time Hour
1
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
10
Detection
Colorimetric
Insulin dependent diabetes mellitus, also called type I diabetes, is a chronic autoimmune disease induced by the selected destruction of insulin producing b-cells of Langerhans` islets caused by autoimmune inflammation reaction. This is characterized by large or complete lack of insulin production. Research has shown that the autoimmune pathogenesis of insulin dependent diabetes mellitus is accompanied by autoantibodies against b-cell antigens. Antibodies against islet cells (32 %) and insulin (up to 70 %), glutamine acid decarboxylase and tyrosine phosphatase IA-2 have also been found. These auto-antibodies have been shown to be a marker for destruction of insulin producing bcells. Anti-insulin antibodies are found in 37 % of subjects with newly detected diabetes type I, in 2-6 % of their relatives of the first degree and in up to 1.5 % of healthy subjects.
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