Mouse / Rat Calprotectin ELISA
$918.00
Catalog
30-6936
The Mouse/Rat Calprotectin ELISA Kit is intended for the quantitative determination of S100A8/S100A9 (Calprotectin, MRP (8/14) in mouse and rat stool, serum, plasma, urine, tissue extract and cell culture supernatant. Research Use Only. Not for Use in Diagnostic Procedures.
Species
Mouse, Rat
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
0.25 - 15.6 ng/mL
Sensitivity
0.076 ng/mL
Sizes
96 Wells
Sample Types
Cell Culture, Plasma, Serum, Stool, Tissue Culture, Urine
Inc Time Hour
4
Inc Time Minute
20
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
100
Detection
Colorimetric
(MRP (8/14) is a calcium-binding protein secreted predominantly by neutrophils and monocytes. Fecal S100A8/S100A9 is a marker for neoplasic and inflammatory gastrointestinal diseases. It is often difficult to distinguish between irritable bowel syndrome and chronic inflammatory bowel disease. This leads in many cases to extensive and unnecessary colonoscopic examinations. The S100A8/S100A9 test allows clear differentiation between the two patient groups. Fecal S100A8/S100A9 levels correlate significantly with histological and endoscopic assessment of disease activity in Morbus Crohn's disease and ulcerative colitis as well as with the fecal excretion of indium-111-labelled neutrophilic granulocytes that has been suggested as the “gold standard“ of disease activity in inflammatory bowel disease. However, measuring 111- indium-labeled granulocytes is very costly (patient’s hospitalization, analysis and disposal of isotopic material) and is connected with radioactive exposition of the patients.
