Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
15-2250 ng/mL
Sensitivity
6.1 ng/mL
Sizes
96 Wells
Sample Types
Plasma, Serum
Inc Time Hour
2
Inc Time Minute
30
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
10
Detection
Colorimetric
Corticosterone is the principle glucocorticoid secreted by the adrenal cortices of mice and rats. Secretion of corticosterone in these species is modulated by a complex negative feedback mechanism involving the central nervous system, hypothalamus, pituitary, and adrenals. ACTH released from the pituitary augments adrenal secretion of corticosterone while falling levels of corticosterone are associated with rising levels of ACTH. In both mice and rats there is a circadian rhythm of corticosterone release with the highest concentrations being observed between 1600 and 2200 hours in a normal laboratory environment.
Research area interests inslcude stress studies, circadian rhythm, endocrinology, metabolic diseases, obesity, and diabetes.
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