Nt-proCNP ELISA
The Nt-proCNP ELISA is an enzyme immunoassay intended for the quantitative determination of nt-proCNP in human serum and plasma (EDTA, Citrate, Heparin).
Features of the assay:
- Includes standards and controls
- Easy-to-follow protocol
- Adaptable for automated systems
Research Use Only. Not for Use in Diagnostic Procedures.
C–type natriuretic peptide (CNP) is a paracrine growth factor widely expressed in tissues, including the vascular endothelium, where it is considered to provide vasoprotective functions. In endothelial cells and macrophages it is secreted in response to several stimuli, including inflammatory mediators. CNP also plays a critical role in linear growth.
CNP is rapidly degraded in tissues and negligible quantities enter the circulation. However, the N-terminal portion of the prohormone is not degraded at the source and circulates in significantly higher concentrations than CNP. Therefore Nt-proCNP is typically measured instead of CNP because of its increased stability and longer half-life.
Research areas include:
- bone metabolism
- non-septic systemic inflammatory response syndrome (SIRS)
- cardiovascular disease
- renal function
This kit number 04-BI-20812 replaces kit 04-BI-20872.
