The Pepsinogen II ELISA is an enzyme immunoassay for the quantitative determination of human pepsinogen II levels in Serum. Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
3 - 300 ng/mL
Sensitivity
0.1 ng/mL
Sizes
96 Wells
Sample Types
Serum
Inc Time Hour
2
Inc Time Minute
20
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
50
Detection
Colorimetric
Pepsinogen consists of a single polypeptide chain of 375 amino acids with an average molecular
weight of 42 kDa. Pepsinogen I is synthesized by gastric chief cells and mucous neck cells, while
pepsinogen II is produced not only by gastric chief cells and mucous neck cells, but also by clear
mucous cells of antrum, etc. The research applications of measuring pepsinogen I and
pepsinogen II include studying severe atrophic gastritis and stomach cancer. It has been
suggested that the measurement of serum pepsinogen may serve as a “serological biopsy” for
predicting the presence of atrophic gastritis or superficial gastritis.
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