The PGF2a ELISA kit is a colorimetric competitive enzyme immunoassay kit for the quantitative determination of PGF2a in culture supernatants, plasma, serum, saliva, and urine from any species with results in < 3 hours. Absorbance is read at 405 nm. Broad dynamic range is suitable for a wide variety of sample types. Ready-to-use liquid color-coded reagents are safe, non-radioactive, and reduce laboratory errors. Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
3.05 - 50,000 pg/mL
Sensitivity
6.71 pg/mL
Sizes
5 x 96 Wells
Sample Types
Cell Culture, Plasma, Saliva, Serum, Urine
Inc Time Hour
3
Inc Time Overnight
No
Inc Time See Protocol
No
Detection
Colorimetric
Prostaglandin F2α (PGF2α) is formed in a variety of cells from PGH2, which itself is synthesized
from arachidonic acid by the enzyme prostaglandin synthetase (3). PGF2α is often viewed as an
antagonist to PGE2 due to their opposing effects on various tissues (4
). PGF2α is a potent bronchoconstrictor and has been implicated in asthma attacks (5, 6). PGF2α is also involved in
reproductive functions including corpus luteum regulation (7), uterine contractions (8), and sperm
motility (9). This has led to its use in terminating pregnancies and inducing labor at term (5, 7, 8, 10).
High levels of PGF2α have also been associated with pre-eclampsia (11). See instructions for use for references.
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