Relaxin ELISA

$1,010.00
Catalog
30-9210
The Relaxin ELISA is for the determination of Relaxin in Plasma, Serum, Urine, Cell Culture, seminal Plasma and Tissue extract. Research Use Only. Not for Use in Diagnostic Procedures.
Species
Human
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
4 - 250 pg/mL
Sensitivity
4 pg/mL
Sizes
96 Wells
Sample Types
Plasma, Serum, Tissue Culture, Urine
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
100
Detection
Colorimetric
Relaxin is a peptide hormone with a molecular weight of 6500Da that belongs to the insulin family. Its main function is the relaxation of smooth musculature. Because of the increased relaxin levels during ovulation and pregnancy most of the knowledge about its physiological properties is gained in the field of gynecology and reproductive sciences. Recently, novel sites of relaxin action have been recognised. In particular, it has been shown that relaxin: (i) promotes dilation of blood vessels in several organs and tissues, including the uterus, the mammary gland, the lung and the heart; (ii) has a chronotropic action on the heart; (iii) inhibits the stimulation of endothelin-1, the most potent vasoconstrictor in heart failure; (iv) inhibits the release of histamine by mast cells, thus being able to counteract experimental allergic asthma; (v) depresses aggregation of platelets and their release by megakaryocytes; (vi) influences the secretion of hormones by the pituitary gland; and (vii) contributes to the regulation of fluid balance. See instructions for use for references.

Relaxin ELISA

30-9210

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