Fecal S100A12 is a novel non-invasive marker which allows the distinction between IBD and Irritable Bowel Syndrome (IBS) as well as viral infections with high sensitivity and specificity.
Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
0.22 - 6.0 ng/mL
Sensitivity
0.016 ng/mL
Sizes
96 Wells
Sample Types
Stool
Inc Time Hour
2
Inc Time Overnight
No
Inc Time See Protocol
No
Sample Size
100
Detection
Colorimetric
The calcium binding protein is expressed in the cytosol of granulocytes and released into the inflammatory tissue. The protein interacts with the RAGE-receptor on endothelial cells, mononuclear phagocytes and lymphocytes and triggers pro-inflammatory processes.
IBD Patients, suffering from Crohn‘s disease or ulcerative colitis exhibit significantly elevated S100A12 levels compared to healthy individuals or patients with IBS.
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