The TXB2 ELISA kit is a colorimetric competitive enzyme immunoassay kit for the quantitative determination of TXB2 in culture supernatants, plasma, serum, saliva, and urine from any species with results in < 3 hours. Absorbance is read at 405 nm. Detect COX I inhibition by measuring the production of downstream TXB2 in a convenient 96 well plate based assay. This kit is highly cited in peer-reviewed publications in a diverse assortment of sample types including mucosa, tissue, serum, plasma, urine, and much more. The TXB2 ELISA kit provides easy-to-use stable liquid color-coded reagents that reduce errors. Research Use Only. Not for Use in Diagnostic Procedures.
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available Worldwide
Range
13.7 - 10,000 pg/mL
Sensitivity
10.54 pg/mL
Sizes
5 x 96 Wells
Sample Types
Cell Culture, Plasma, Saliva, Serum, Urine
Inc Time Hour
3
Inc Time Overnight
No
Inc Time See Protocol
No
Detection
Colorimetric
Thromboxane A2 (TXA2) is involved in platelet aggregation, vasoconstriction, and reproductive
functions (3-5). However, TXA2 has a half-life of only 37 seconds under physiological conditions (5),
and the production of TXA2 in vivo is typically monitored by measurement of TXB2 and 2,3-dinor
TXB2. Thromboxane B2 (TXB2) is produced by the non-enzymatic hydration of TXA2, and has been
shown to be stable (6,7). A number of pharmaceuticals alter and/or inhibit the synthesis of TXA2
(8-10) and methods to determine TXA2 in urine and blood typically involve gas chromatography/mass
spectrometry11, radioimmunoassay, or enzyme-linked immunoassay. See instructions for use for references.
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